Archive for January, 2011

True Grit and Grace

Monday, January 31st, 2011

Exactly six months ago, I shared a blog with Melanoma Updates readers, written by a woman chronicling her battle with Melanoma.  I shared her story because I was impressed by her good attitude, helpful information, and generosity of spirit, and thought her blog would be helpful beyond her small community in Cyprus.  Her name is Alethea Ayers and she is the 35 year old mother of a toddler.

While there are, sadly, many victims of skin cancers and Melanoma — hence the existence of Melanoma Updates and our goal of driving awareness and preventative actions,  Alethea is one who has been inspiring and very public about her battle with the disease.

Now that battle has faced a two-sided assault:  she has received news of some 10 brain tumors, and is also fighting to raise the funds to travel from Cyprus to Germany for more advanced treatments.  As a physician I can say that this kind of metastasis is unfortunately statistically common in Melanoma patients, and survival rates are statistically unsatisfying.  You can read more on brain metastases on the Skin Cancer Foundation Web site.Alethea Ayers

I can tell you I don’t know Alethea, and have not vetted her case or her cause, but between her Facebook page and very specific blog posts I find her story and attitude very compelling and worth the read… and perhaps a contribution.   That is a personal decision, and there are many worthy causes we could all support.  At the very least, I want to share her very human emotions in her latest post here, filled with reminders of what we’ve been touting at MoleSafe as well:

Getting hopeful with every passing day as it means a day closer to when I can start my treatment. I can’t wait till they start shrinking these darn things and I can start a normal life again.

No one teaches you in school or as you grow up what do to in these situations, there’s no break glass in case of emergency and there is no instruction manual on what to do in case you get brain tumours.  So I live every minute by the minute and make it through the day with all your wonderful help.

All I ask that you please please avoid sunbeds, and sunbathing. Please love the skin you are in. Milk bottle white, means you are alive and will be alive. Life is too precious.

Love the skin you are in.

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On Common Ground: Applying “Open Source” to Cure Melanoma

Tuesday, January 18th, 2011

Most doctors feel for their patients and we empathize with the challenges of their illness.  We work to the best of our experience and understanding to find cures, solutions, or sometimes just more comfort.  But when it comes to big challenges, such as advancing treatment options for diseases like Melanoma, sometimes empathy is not enough.  Sometimes what sparks the motivation to find solutions or cures is personal experience….

That is what spurred e-commerce entrepreneur, Marty Tennenbaum.  While he’s not a doctor or even medical researcher, he does know his way around computers, and the value of “open source” as a route to developing solutions.  So, after surviving Melanoma in the late ’90s he begin applying his expertise to help move the needle on treatment solutions.

Many scientists today work in relative isolation, left to follow blind alleys and duplicate existing research. Data are fragmented — trapped behind firewalls, locked up by contracts or lost in databases that can’t be accessed or integrated. Materials are hard to get — universities are overwhelmed with transfer requests that ought to be routine, while grant cycles pass and windows of opportunity close.

Marty recognized that dilemma and his doing his part to use his tech know-how to bring about a tool to help solve that problem:  An app.

Dr. Marty Tenenbaum, a survivor of melanoma, shows off his free Cancer Commons app

Dr. Marty Tenenbaum, a survivor of melanoma, shows off his free Cancer Commons app

Launching today (1/18/11), the “Cancer Commons” app will integrate existing data about melanomas, and cross reference promising experimental treatments.   Then, patients or doctors can in put patient-specific info on the progression of the disease including test results, such as specific genetic mutations.

“From that information, the app tells patients what specific cancer “subtype” they have as determined by an expert panel. They also learn what drugs have shown the most promise in treating that specific form of the disease and where clinical trials are being conducted that could allow patients access to that treatment.”

Marty explains that he’s just “trying to pull together all the pieces that are needed to do a real, rational attack on cancer.”

…’The way to do that,’ he says, ‘is to pull people out of their individual labs, offices and hospitals to collaborate in a way not possible before the Web and mobile technologies made it easy to pool vast amounts of information.

‘How much of cancer could be turned into a manageable disease if we only knew what we knew?’”

It’s a challenge to wrap our arms around the collected knowledge of thousands of researchers.  Groups like Health Commons and Open Science are taking a page from today’s socially networked world to tap that trust and are working to throw open the doors to the brain trust.  MoleSafe and Melanoma Updates applauds this approach, and gives Marty Tennenbaum and the collected participants pitching in a big Hat’s On Award to helping shine the light on the way to a cure for Melanoma and other cancers.

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Shining the light on Vitamin D

Thursday, January 6th, 2011
It’s pretty common knowledge by now that sun on human skin leads to the production of Vitamin D, which has been touted for reducing the risk of everything from Type 2 Diabetes to many cancers.  So, with science’s increased recommendations to avoid the sun and increase regular use of sunscreen there has been some concern that we would have a deficit of this nutrient. Not only is this concern unjustified, it is a slippery slope to rationalizing the “need” for a tan. For example, an article in Allure Magazine, which I wrote about recently, discussed the dangers of tanning.
But one young woman, “Katie_k”, who posted a comment, had convinced herself that her tanning salon use was justified by the need for Vitamin D.    Here’s what I wrote to her in response:

This article is important.   And to Katie_k who vowed to continue using tanning beds out of concern about low Vitamin D scares:   My answer? You’re wrong. The fact is, we can now check our  vitamin D level and take supplements should we be found to be deficient.  Skin cancer is nothing to be messed with. Exposing ourselves to a carcinogen like UV rays is never a good idea. Using a tanning bed is especially a bad one.

I am concerned about the Katie_ks of the world. So here’s a reminder from a good summary article, to try again to allay fears about a lack of Vitamin D:

“For most children, teens and adults, a daily dose of 400 international units (IUs) of the vitamin is sufficient, and 600 IUs are recommended. Seniors older than 70 should ideally receive 800 IUs of vitamin D a day, the panel determined. For babies younger than 1, the panel considered 400 IUs of vitamin D enough.

Those levels are somewhat higher than the ones set in 1997, the last time a government panel examined vitamin D intake. But they are far below what many doctors and supplement advocates had been urging….

Does that mean I should give up my vitamin D supplements?

Maintaining a healthy level of vitamin D through diet alone has become much easier since manufacturers began fortifying foods with the nutrient. Fortified foods — including virtually all milk, many brands of orange juice, and some cheeses, yogurts, margarines and breakfast cereals — are now some of the richest dietary sources of vitamin D. High levels exist naturally in fatty fish such as tuna, salmon and mackerel, and it’s also present in egg yolks and beef liver….

Indeed, the sun is a free, plentiful source of vitamin D. When the sun shines on human skin for at least five to 15 minutes, the body produces the nutrient. But with people spending more time indoors and using sunscreen to prevent skin cancer, this source has fallen on hard times. In fact, the panel didn’t even factor in vitamin D from sun exposure when it made its recommendations.

Does that mean I should lay off the sunscreen?

The sun can be a powerful manufacturer of the nutrient: In 15 minutes, a light-skinned person wearing a bathing suit outside in early July will produce 15,000 to 20,000 IUs of Vitamin D.

The body stores excess vitamin D in fat, and some research suggests that it is released as needed. But there’s debate about how well that happens, so the panel members suggest that daily dosing of vitamin D is a better bet.

Besides, even 15 minutes without sunscreen won’t fly with dermatologists. They warn that prolonged exposure to ultraviolet light – either from the sun or in a tanning booth – elevates a person’s risk of developing melanoma, the deadliest form of skin cancer. So, by all means, slather on that sunscreen.”

Do read the whole story.  Here’s a link to that and another good story about Vitamin D.

So, drink your fortified milk and toast to your good health.

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